Abstract: A method based on motion capture technology is proposed to deal with airfoil deformation measurement under real-time dynamic conditions. Firstly, high-precision motion capture technology is used to obtain the absolute coordinate data of the physical marker points on the airfoil surface in real-time. Secondly, Using a mesh deformation interpolation algorithm based on Laplacian coordinates, the digital model of the airfoil and the coordinate information of the physical marker points are used for interpolation to obtain the real-time coordinates of the mesh vertices of the digital model. Finally, by comparing the difference between the coordinates of the mesh vertices and the initial coordinates, the real-time deformation information of the airfoil is obtained to complete the measurement of the airfoil deformation. The proposed method is compared with the inverse distance weighting on two motion capture data, and the results show that the deformation of the airfoil can be measured in real time with high accuracy, and the measurement error does not exceed 1 mm.