Abstract: Biomacromolecules,such as proteins and nucleic acids,affect the microscopic behavior of beings and directly determine the life functions of species.The visualization technology of biomacromolecule structure has large significance in the field of molecular biology and biochemistry,and is an important re-search direction of computer-aided drug design.In this paper,the visualization of biomacromolecule struc-ture in recent years is deeply investigated and analyzed.First of all,the concept of molecular skeleton,sur-face and cavity and the basic visualization methods are summarized based on the definition of molecular spatial morphology.Secondly,the recent large-scale visualization technologies of biomolecule scene,in-cluding molecular assembly,LOD and GPU acceleration,are discussed.Thirdly,the visual analysis tech-niques of dynamic molecular structure are shown,which includes visual analysis of molecular trajectories and dynamic cavities.Then,the visual interaction technologies of biomolecules for virtual reality is intro-duced.Finally,the challenges faced by the visualization of biomacromolecular structures are summarized,and the future development trend is prospected.