Abstract: To extract three-dimensional facial wrinkles and assess the degree of facial wrinkles accurately and objectively, a three-dimensional detection approach of facial wrinkles based on the curve fitting method with continous first derivation is proposed. The approach simulates the growth procedure of facial wrinkles and treats the field of facial wrinkles as the composition of wrinkles and sleek curve. The parameters including number of wrinkles, overall average wrinkle depth, average largest wrinkle depth and absolute wrinkle area are used to quantify facial wrinkles under the consideration of the subjective judgment approaches and the three-dimensional features of facial wrinkles. The experimental results of facial forehead and facial periorbital area show that the approach in this paper can illuminate the three-dimensional details of facial wrinkles and is not affected by the light and direction easily. The approach achieves three-dimensional extraction and quantification of facial wrinkles.