Abstract: Pixels of different columns in the infrared focal plane array（FPA） have different readout channel,amplifiers in different readout channel have different 1/f noise characteristics.Such noise may cause heavy stripe noise in the infrared images and degrade the quality of captured images.In this paper,a stripe noise removal method using guided filter is proposed.First,the average row vector of the blurred image is obtained by moving images,then the stripe noise correction term is extracted from average row vector using guided filter;finally,the infrared images are corrected by the noise correction term.Experiment shows that the proposed method removes stripe noise efficiently and exhibits better performance than other method discussed in literature.