Abstract: At present, in Electrical Wiring Interconnection Systems (EWIS), there is a lack of high-quality automatic cable layout methods, and a few public methods mostly use direct wiring methods. The applicability of these methods is narrow, it is difficult to meet the constraints of auxiliary process, and the efficiency is low. Therefore, based on engineering practice, this paper presents the EWIS cable automatic layout method based on channel design. Considering the relaxation, bending radius, interference, spacing, electromagnetic isolation and other complex constraints, the routing strategy is proposed to first design the channel and then design the specific cable layout. A series of innovative and practical methods are proposed in channel design: kd-tree is used to search the nearby wiring clamp points efficiently; The generalized cable path evaluation function is proposed, which integrates the complex process constraints such as inclination angle, length and spacing. Use greedy thinking to build high quality channels. On the basis of channel design, the branch point design of cable is further carried out (the process requires avoiding the clamp as the branch point), and the diagram model of the branch point is established. Finally, a single cable layout is designed one by one, loops that do not meet the process are detected, channels are updated, and the overall cable layout is iterated to complete. The experimental results on automatic routing  test results show that the wiring effect of the proposed method is more regular, and compared with manual wiring, the proposed method reduces the length of the cable, the number of turns and the number of branches by 25.0%, 25.1% and 30.1% on average, indicating the effectiveness of the proposed method.